| A high blood cholesterol is said to promote atherosclerosis and thus also coronary heart disease. But many studies have shown that people whose blood cholesterol is low become just as atherosclerotic as people whose cholesterol is high. Atorvastatin is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in your blood. Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the There is no evidence that too much animal fat and cholesterol in the diet promotes atherosclerosis or heart attacks. For instance, more than twenty studies have shown that people who have had a heart attack haven't eaten more fat of any kind than other people, and degree of atherosclerosis at autopsy is unrelated with the diet. The new cholesterol-lowering drugs, the statins, do prevent cardio-vascular disease, but this is due to other mechanisms than cholesterol-lowering. Unfortunately, they also stimulate cancer in rodents. Atorvastatin is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in your blood. Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the Evidence from the new cholesterol-lowering trial PROSPER, that statin treatment causes cancer. If you take Atorvastatin with certain other medicines, they may affect one another. Atorvastatin may interact with certain other cholesterol-lowering drugs, some antibiotics, and antifungal medications. It may also interact with less-frequently prescribed medications as immunosuppressives (given after transplants). Be sure to tell your doctor or pharmacist about all prescription and nonprescription drugs you are taking. Atorvastatin is generally well tolerated and side effects are usually mild. In studies, the most common side effects associated with Atorvastatin were constipation, flatulence, indigestion, and abdominal pain. If you are prescribed Atorvastatin, your healthcare professional may want to conduct routine blood tests to check your liver function before and after starting treatment. Be sure to tell your healthcare professional if you have any allergies to food or medication. Also, report promptly any unexplained muscle pain, tenderness, or weakness, particularly if accompanied by discomfort or fever, as these symptoms may be signs of serious side effects. Generally, Atorvastatin works within 2 weeks. The full effect is usually seen within 4 weeks and lasts as long as you continue taking it. Always take Atorvastatin as directed by your healthcare professional. Read Dr. Ravnskov´s thought-provoking paper "High cholesterol may protect against infections and atherosclerosis", recently published in the prestigious Quarterly Journal of Medicine How long does it take Atorvastatin to work? Atorvastatin is a very effective medicine for lowering high LDL cholesterol—the main target of cholesterol-lowering therapy. Your doctor will determine how much your LDL cholesterol needs to be lowered, based on your overall risk of heart disease. Atorvastatin also effectively lowers high blood-triglyceride levels. If you take Atorvastatin with certain other medicines, they may affect one another. Atorvastatin may interact with certain other cholesterol-lowering drugs, some antibiotics, and antifungal medications. It may also interact with less-frequently prescribed medications as immunosuppressives (given after transplants). Be sure to tell your doctor or pharmacist about all prescription and nonprescription drugs you are taking. Your body produces three to four times more cholesterol than you eat. The production of cholesterol increases when you eat little cholesterol and decreases when you eat much. This explains why the ”prudent” diet cannot lower cholesterol more than on average a few per cent. The following Information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. In medical studies of people with high cholesterol, Atorvastatin, taken once a day, had the following effects at doses of 10 to 80 mg: Lowered total cholesterol by 29-45%. Lowered LDL cholesterol, the "bad" cholesterol, by 39-60%. Increased HDL cholesterol, the "good" cholesterol, by 5-9%. Lowered triglyceride levels by 19-37%. The new cholesterol-lowering drugs, the statins, do prevent cardio-vascular disease, but this is due to other mechanisms than cholesterol-lowering. Unfortunately, they also stimulate cancer in rodents. |